Inside the Obriens

Joe O'Brien, a third-generation Irish cop in Charlestown, faces a life-altering diagnosis of Huntington's disease that forces him to confront losing his career, his identity, and his sense of purpose. As his symptoms progress and Joe gradually loses his badge and independence, his daughter Katie and her three siblings must grapple with a devastating choice: undergo genetic testing to learn their own fate or live in uncertainty. Lisa Genova explores how one family navigates the physical and emotional weight of hereditary illness, testing bonds of love and resilience across generations.